Particle Knife Therapy

New Options other than Surgery, Radiotherapy and Chemotherapy

According to statistics, over forty years from 1972 to 2014, the three traditional treatments have always been dominated in the area of cancer treatment. However, the valid life extension of cancer patients has just increased less than 5%. This indicates that cancer treatment needs new concepts and new approaches. Minimally invasive treatment for cancer is born in such cases. For cancer patients, treatment opportunity is so precious, because many treatments can only get one chance. As a result, many patients feel desperate after having surgery, radiotherapy, chemotherapy or meeting with recurrence and metastasis, as if their life is over. Is it their only option to wait for the end of their life? The answer is definitely NO! The development of modern medical technology has brought a new option for cancer patients——Particle Knife Therapy.

What Is Particle Knife Therapy?

Particle Knife Therapy is to implant the radioactive particles into tumors with the help of computer Treatment Planning System. The particles which release γ-rays can continuously kill tumor and cause destruction targeting tumor cells. With time, the radiation amount would accumulate to be large enough to destroy the DNA double strands of tumor cells. Particle knife therapy is a short-distance minimally invasive therapy, which not only can kill the tumor cells, but also can prevent the surrounding normal tissues from being damaged. For patients in late-stage cancers, it can prolong their life span and release their pain from cancer; for those in early or middle stages, it can extremely increase the thoroughness of treatment.

Nowadays most scholars believe that chemotherapy is gradually transit from palliative therapy to radical treatment. The traditional systemic chemotherapy is weak in selective inhibition of tumor cells, which has larger toxicity and destructiveness to the immune system. While particle knife therapy can implant radioactive particles into tumors accurately mainly depend on stereotactic system and release continuous and short-distance radioactive rays through micro radioactive source, which can subject maximum damage to tumor tissue, but tiny or no damage on normal tissues.

The number of particles implanted is up to the size of the tumor, even some tumors may disappear after one time of implantation. If the recheck found that the implanted quantity is not enough, you can do the implantation again to make complement. The radioactive half-life of particles is 60.1 days, so the effective radiation effect will last for 180 days in human body after one implantation.

The particles which release γ-rays can continuously kill tumor and cause destruction targeting tumor cells. With time, the radiation amount would accumulate to be large enough to destroy the DNA double strands of tumor cells. Consequently, to kill cancer cells by radioactive particles is a continuous and slow process. General, tumor cells will have obvious necrosis after 2-3 months after implanting the particles. For tumors on the body surface, patients can clearly see their shrink; for those inside the body, patients can see their shrink or necrosis by CT Scan or B-ultrasonic examination.

The effective range of the particle rays is 1.7 CM, its radiation damage to doctors and patients is far lower than the national protection standards, so patients don’t have to worry about the radiation safety. What patients should notice is that within 2 months after particle implantation, please try to avoid close contact with pregnant women or children under the age of 3. After 2 months, the radiation rays will gradually wear off and patients can return to their normal life. The shell of radioactive particles is made of titanium alloy, which is not affected by magnetic field, so even after the radioactive particles are implanted into human body, they still can do examinations such as CT scan, MRI, X-ray, ultrasonic, etc.as usual.

Four Advantages of Particle Knife Therapy

Strongly Targeted and Significant Effect

The radioactive particles implanted in tumors can concentrate on effectively killing tumor cells and make tumors shrink or disappear.

Small Damage and No Complications

The particles implanted can only kill tumor cells within 1cm from the radiation source, but no damage to other body tissues, which can effectively improve the recovery of cancer patients.

Small Trauma and Quick Recovery

Generally, radioactive particles will be implanted under the guide of B-ultrasonic and CT scan, or in the process of operation, which will just lead to small trauma and light feeling of pain.

Effective Method of Comprehensive Treatment

Particle implantation can work together with other treatments such as surgery and chemotherapy, which will improve the curative effect of surgery and shorten the course of chemotherapy.

Three Steps of Particle Knife Therapy

Particle Knife
Precisely Implant the Radioactive Particles

First decide the number of implanted particles and their location according to the size and location of the tumors, then under the guide of ultrasound, using puncture needles to precisely implant the particles into the tumor.

Particle Knife
Shrink Tumors by Internal Radiation

The particles implanted into the tumor will produce γ-rays, which can kill tumor cells and lead to necrosis of the surrounding tumor tissues, but the normal tissues will almost not be damaged. Thus to achieve the purpose of shrink the tumor.

Particle Knife
Eliminate Tumors by Sustained Radiation

The effective radius of radioactive particles is 1.7cm, and with the radioactive half-life of 60.1 days, the γ-rays they release can cover the tumor and its subareas. After continuous radiation effect to the tumor, the tumor will finally disappear.

Who are the Applicable Patients of Particle Knife Therapy?

  1. Primary tumors which haven’t been treated, such as prostate cancer;
  2. When it’s needed to keep the important functional tissues, or having surgery will affect the important organs, such as brain tumors;
  3. Cases in which patients are reluctant to conduct radical surgery, such as thyroid cancer, endometrial cancer, cervical cancer, etc;
  4. Patients with metastatic tumor lesions or postoperative isolated tumor metastases, who are not worthy to have operations, such as multiple-metastasis lung cancer;
  5. Primary tumors which can’t do surgery, such as massive liver cancer, nasopharyngeal cancer, etc;
  6. Prevent the local or regional spread of tumors, enhance the radical effect, that is, prophylactic implantation, such as retroperitoneal tumor;
  7. Cases in which it is ineffective or defeated in having radiation therapy.

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